Persistent exhaustion, trouble breathing, confusion, loss of memory

If you or someone close to you has been diagnosed with heart failure and functional mitral regurgitation (FMR), you may already be struggling with some of these debilitating symptoms. You may be exhausted just preparing a meal, getting out of bed, walking across the room, or climbing stairs.

There is no cure for heart failure and FMR. Your doctor may prescribe medications to help treat symptoms. Implanting a pacemaker or a left ventricular assist device may temporarily improve function and slow symptom progression. Some patients may be eligible for open-heart surgery to repair or replace valves in the heart. Far fewer will receive a transplant.


What is Heart Failure?

Heart failure is a condition in which your heart’s muscles slowly weaken and lose their ability to pump enough oxygen-rich blood to the body.


What is Functional Mitral Regurgitation (FMR)?

In a healthy heart, the mitral valve acts like a door to prevent leakage between the left ventricle and left atrium. An enlarged left ventricle is common among heart failure patients. As it expands, the weakened heart wall stretches the opening of the mitral valve and allows blood to flow backwards into the atrium.

Mitral valve dysfunction caused by an enlarged left ventricle is called functional mitral regurgitation (FMR), and it exacerbates the symptoms of heart failure. Up to 74% of people with heart failure also suffer from FMR.2


  • Footnotes

    1 Mozzafarian D, Benjamin EJ, Go AS, et al. on behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics—2016 update: a report from the American Heart Association. Circulation. 2016;133:e38-e360.
    2 Al-Amri, H. S., Al-Moghairi, A. M., & El Oakley, R. M. (2011). Surgical treatment of functional mitral regurgitation in dilated cardiomyopathy. Journal of the Saudi Heart Association, 23(3), 125–134.


with AccuCinch

Ancora Heart developed AccuCinch as a new treatment option for the millions of heart failure and FMR patients who are unlikely to survive the risks of open-heart surgery.

AccuCinch is the first of a new class of therapies that repairs the left ventricle and directly targets the cause of heart failure and FMR.

Leading heart centers are studying the AccuCinch system’s ability to repair and reshape the enlarged left ventricle. AccuCinch has the potential to be the first therapy to target the primary cause of FMR and heart failure and enable patients to feel better.


How it works

Step 1

The transcatheter AccuCinch procedure reshapes the enlarged left ventricle by implanting the AccuCinch device in the heart wall to improve left ventricular function, reduce FMR, alleviate symptoms of heart failure, and enhance quality of life for patients.

Step 2

During the procedure, a catheter is guided through the aortic valve to reach the left ventricle. A series of anchors are implanted in the left ventricle below the mitral valve. A cable connects the anchors and is cinched in place.

Step 3

Once cinched, the left ventricular size is reduced, the heart wall is strengthened, and symptoms of heart failure and FMR are alleviated.


Find out if AccuCinch may be right for you

Ancora Heart is currently enrolling patients in clinical trials to evaluate AccuCinch in the U.S. and Europe. Click to download a brochure to review with your doctor.


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